British Short Hair 

Polycystic Kidney Disease (PKD)

 

Polycystic Kidney Disease (PKD) is a genetic condition that affects a variety of cat breeds, including British Shorthairs. This disease is caused by an autosomal dominant gene mutation, meaning that only one copy of the affected gene is required for a cat to develop PKD. If a cat carries the PKD gene, there is a 50% chance that the gene will be passed on to its offspring.

PKD is characterized by the development of fluid-filled cysts in the kidneys, which can gradually enlarge and impair kidney function over time. While PKD is most commonly associated with Persian cats, research has shown that it can also occur in other breeds, including British Shorthairs.

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Cats with PKD may live many years without showing any symptoms, but as the disease progresses, it can lead to chronic kidney failure. Symptoms of kidney disease in affected cats can include increased thirst, frequent urination, lethargy, and weight loss. However, it's important to note that the onset and severity of PKD can vary widely, even among cats with the same genetic mutation.

Fortunately, PKD can be detected through a simple DNA test, which can be performed at any age. This test identifies whether a cat carries the PKD gene mutation, helping breeders make informed decisions to avoid passing the condition to future generations.

For cat owners and breeders, early detection through genetic testing is crucial in managing PKD and ensuring the health and well-being of their cats. If you suspect that your British Shorthair or other cat might be at risk for PKD, consult your veterinarian about getting a genetic test.